Subclinical Left Ventricular Dysfunction in Asymptomatic Type 1 Diabetic Children

J Cardiol Curr Res 2016, 6(6): 00229 measurement of left ventricular ejection fraction (LVEF) using standard two-dimensional (2D) echocardiography [2,3]. However, the LV contractility is a complex mechanism resulting from a three-dimensional structure. Myocardial fibers are orientated in different directions and responsible for three principal types of deformation: longitudinal; radial and circumferential deformation [4]. Myocardial strain assessment based on 2D speckle tracking analysis is a novel echocardiographic approach for a sensitive and angle-independent evaluation of myocardial deformation and an able tool to evaluate the three components of myocardial deformation. It has been shown to be the most sensitive echocardiographic tool for the detection of sub-clinical impairment of myocardial function observed in many conditions such as aortic stenosis, hypertrophic myocardiopathy and hypertension. The objective of this study was to characterize global systolic function abnormalities using 2D Strain in T1D children and to assess the relationship between these myocardial data and glycemic control.